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Dinafex 50ml
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Dinafex 50ml

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55.00৳ 

30 mg/5 ml
50 ml bottle: ৳ 55.00
Dinafex 50ml

55.00৳ 

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Description

Pharmacology

The H1 histamine receptor is responsible for mediating hypersensitivity and allergic reactions. Exposure to allergen results in the degranulation of mast cells and basophils, which then release histamine and other inflammatory mediators. Histamine binds to, and activates, H1 receptors, which results in the further release of pro-inflammatory cytokines, such as interleukins, from basophils and mast cells. These downstream effects of histamine binding are responsible for a wide variety of allergic symptoms, such as pruritus, rhinorrhea, and watery eyes.

Fexofenadine is considered an “inverse agonist” of the H1 receptor because it binds to and stabilizes the inactive form of the receptor, preventing its activation and subsequent downstream effects. It has a potent and selective affinity for H1 receptors, and there is no evidence that it carries antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity. Fexofenadine does not cross the blood-brain barrier and thus is unlikely to cause significant CNS effects.

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Return & Refund Policy – Maleka Pharma

This Return & Refund Policy explains the terms under which medicines purchased from Maleka Pharma can be returned or replaced, ensuring customer safety and regulatory compliance.

  • Customers must have a registered mobile number ID to request any return or replacement.
  • If any medicine is sold above the printed Maximum Retail Price (MRP), customers should inform the authority immediately.
  • Medicines are eligible for return or replacement within 30 days from the date of purchase, subject to verification.
  • The expiry date section on the medicine strip or package must remain intact at the time of return.
  • The following items are not eligible for return or replacement:
    • Insulin
    • Vaccines
    • Refrigerated items
    • Cut or opened medicines
  • The original cash memo is mandatory. Returns or refunds without a valid cash memo will not be accepted.

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Dinafex 50ml

55.00৳